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Medical professional using Cryo PainBlocker™ cryoanalgesia device by Epimed for minimally invasive pain management.

Expand Your Treatment Options with Cryoanalgesia: Introducing the Cryo PainBlocker™

Chronic pain requires effective, long-term solutions that go beyond temporary relief. At Epimed, we are committed to offering pain specialists the tools they need to treat patients confidently and precisely. Our Cryo PainBlocker™ system is at the forefront of cryoanalgesia, a well-established technique that provides sustained pain relief while preserving nerve function.

What Is Cryoanalgesia?

Cryoanalgesia (or cryoneurolysis) is a minimally invasive pain management technique that uses extremely cold temperatures to freeze targeted peripheral nerves, temporarily interrupting pain signal transmission. Unlike other neurodestructive procedures, cryoanalgesia preserves the structural integrity of the nerve, allowing for natural regeneration and avoiding neuroma formation.
Clinical studies support the use of cryoanalgesia in chronic pain, with reports of pain relief lasting up to 1.7 years after a single procedure.*

Clinical Indications for the Cryo PainBlocker™ System

Cryoanalgesia with the Cryo PainBlocker™ is indicated for numerous neuropathic and post-surgical pain syndromes, including:
• Intercostal neuralgia
• Occipital neuralgia
• Ilioinguinal, iliohypogastric, and genitofemoral neuralgia
• Post-thoracotomy and post-herniorrhaphy pain
• Neuromas and neuritis
• Trigeminal neuralgia
• Ganglion of impar
• Phantom limb pain
• Facet-related axial spine pain
• Coccydynia
• Peroneal and obturator neuralgia
• Cluneal neuralgia
• Genicular nerve pain
• Glossopharyngeal neuralgia
• Plantar fasciitis and fibromas
• Other peripheral neuropathies
Refer to the Product Information Guide (PDF) for complete indications and procedural recommendations.

Why Choose the Cryo PainBlocker™?

Designed for precision and ease of use, the Cryo PainBlocker™ by Epimed is an advanced cryoanalgesia system that delivers fast and effective pain relief with minimal trauma. Here’s why it’s gaining momentum among interventional pain physicians:

Minimally Invasive
The Cryo PainBlocker™ requires minimal anesthesia, can be performed percutaneously, and does not require sutures. This makes it ideal for outpatient settings.

Immediate Pain Relief
Patients experience little to no post-procedure discomfort, and recovery time is virtually nonexistent.

Simple and Safe
The procedure is typically completed in one session with minimal post-operative bruising. It’s a low-risk, high-benefit option for long-lasting pain management.

Versatile Cryoanalgesia System

The PainBlocker™ system offers a complete line of cryoprobes in various lengths, diameters, and tip configurations to match your procedural needs. Whether you’re treating intercostal neuralgia, occipital neuralgia, or post-surgical neuropathies, Epimed provides the flexibility you need for precise cryoablation.
Explore our full Cryoanalgesia product line and discover how you can tailor treatments to each patient.

Clinical Evidence Supports Cryoanalgesia

Cryoanalgesia has been shown to provide significant and prolonged pain relief in various clinical settings. Studies highlight its non-opioid mechanism, making it a powerful alternative in modern pain medicine.
📄 Read our featured clinical report on cryoanalgesia efficacy and outcomes.
*Data on file.

Train with Experts at the Racz Lab

Want to expand your procedural skills? Join us at the Racz Lab Workshop in Dallas, TX, on April 4–5, 2025, for hands-on training with top physicians in interventional pain management.
Participants will get direct experience using the Cryo PainBlocker™ and other advanced techniques under expert guidance.

🔗 Learn more about the Racz Lab Workshop

Experience Cryoanalgesia. Trust Epimed.

From high-performance probes to expert training and clinical support, Epimed is your partner in cryoanalgesia. The Cryo PainBlocker™ enables you to offer safe, effective, and long-lasting pain relief—without compromising nerve integrity.

Ready to integrate cryoanalgesia into your practice?
Contact us today.

FAQs: Cryoanalgesia with Cryo PainBlocker™

Q1: How does cryoanalgesia compare to thermal radiofrequency ablation?

Unlike thermal RF, cryoanalgesia induces reversible axonotmesis without coagulative necrosis, preserving the nerve’s structural integrity and reducing the risk of neuroma formation.

Q2: What is the average duration of pain relief achieved with cryoanalgesia?

Pain relief typically lasts between 3 and 12 months. In some cohorts, relief has been documented for up to 20 months following a single cryoablation session.

Q3: Can cryoanalgesia be billed under standard interventional CPT codes?

Our Physician Services department can assist you with coding guidance and payer-specific reimbursement information.

Q4: What types of pain can be treated with the Cryo PainBlocker™?

The Cryo PainBlocker™ is used for a range of peripheral neuropathic pain conditions, including intercostal neuralgia, occipital neuralgia, ilioinguinal and genitofemoral neuralgia, and post-surgical pain. A full list of indications is available in the product guide.

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